3. cAMP a… Show more True or False 1. PLC will generate IP

3. cAMP a… Show more True or False 1. PLC will generate IP3 and DAG from PIP3. ( ) 2. Calcium inhibits PKC. ( ) 3. cAMP activates PKA. ( ) 4. Delta binds to Patched. ( ) 5. TGFβ signal stabilizes beta-­‐catenin transcription factor. ( ) 6. The Notch tail can function as a transcription factor. ( ) 7.Wnt signaling destabilizes β-­‐catenin through GSK3 mediated phosphorylation. ( ) 8. Pertussis toxin modifies Gαi protein. ( ) 9. MAP kinase activates MAP kinase kinase (MAPKK). ( ) 10. cAMP is an example of a second messenger. ( ) 11. Adherence junction is enriched with intermediate filaments. ( ) 12. Intermediate filaments are permanent structures that cannot be dissembled in any case. ( ) 13. Plectin cross-­‐links only the intermediate filaments. ( ) 14. β-­‐Tubulin has an ATPase activity. ( ) 15. ARP2/3 is the nucleating protein for the 70o degree branched microtubule structures. ( ) 16. Formin is the nucleating protein for the branched filamentous actin structures. ( ) 17. Thymosin binds to a tubulin dimer, and prevents its addition to the plus-­‐end. ( ) 18. EB1 binds to the minus end of the microtubule. ( ) 19. Microtubules can be severed in the middle by severing proteins such as Gelsolin. ( ) 20. A molecular motor Dynein moves to the positive end of the microtubule. ( ) 21. Actin has a GTPase activity. ( ) • Show less

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