K.S. comes for a clinic visit to determine whether she is pr

K.S. comes for a clinic visit to determine whether she is pregnant. She is very concerned because sh… Show more K.S. comes for a clinic visit to determine whether she is pregnant. She is very concerned because she suspects there may be a genetic disease in her family. On further questioning, you find out that her brother’s son has the disorder. Her brother’s other children (a boy and a girl) are unaffected. K.S.’s parents, grandparents, and other siblings (a brother and two sisters) do not have manifestations of the disorder. Her brother’s wife has said that she thinks one of her distant relatives may have had the disease. If the disorder is indeed inherited as a single-gene defect, which of the following inheritance patterns is/are the most probable? (select all that apply) X-linked dominant Autosomal Dominant Autosomal recessive X-linked recessive Construct a pedigree chart and based on that chart, what is the likelihood that K.S. has the defective gene? (select all that apply) 25% chance of carrying the affected gene. 0% chance of carrying the affected gene. 75% chance of carrying the affected gene. 50% chance of carrying the affected gene. • Show less

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