Suppose that you compare the levels of nonsynonymous and syn

Suppose that you compare the levels of nonsynonymous and synonymous substitutions (i.e. you perform… Show more Suppose that you compare the levels of nonsynonymous and synonymous substitutions (i.e. you perform the kA/kS test) on a particular coding region of a gene. You find that kA/kS = 0.3. (a) What type of selection, if any, would this result support? (b) You also examine levels of polymorphism around this particular gene in a sample of 20 individuals from the population of interest. You find that Tajima’s D is -2.8. What type of selection, if any, would this result support? (c) Provide 2 explanations for why the kA/kS test and the Tajima’s D test appear to give contradictory results. • Show less

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